More or less dice?

I have a large collection of dice, of various shapes and sizes, and I know I'm not the only tabletop gaming hobbyist who will gladly buy a die that I've never seen before, if it's in the bin at my FLGS. The most fun for me seem to be those that I know I'll never use. Among these are a pair of d6's that are numbered 2, 3, 3, 4, 4, 5 (supposedly used for bite damage in the old Vampire: The Masquerade); another pair of translucent d6's that each have a tiny d6 inside them; a twenty-sided die numbered 1 to 5 four times; and several "old-school" twenty-sided d10's (two of which I actually use as percentile dice).

Mine are red with white numbers, and white with red numbers,
respectively; this makes them perfect for percentile rolls!

Whenever I decide to work on my own tabletop game, I wonder if I should have it use as many different types of dice as possible (i.e. the normal set of polys), or as few as possible (only d6's or d10's). On the one hand, some people like rolling various sizes and shapes of dice, due to how certain actions have a different "feel" from others. On the other hand, having a game that only relies on percentile rolls and d10 rolls (maybe along with 2d10) would be much more portable, and the idea of a "core mechanic" is not entirely a bad one.

At the extreme of different dice types is Dungeon Crawl Classics, to the point where Goodman Games actually sells a pack of the weirdest dice I've ever seen, mixed in with the standard Platonic solids. They can be found at the bottom of this page: http://www.goodman-games.com/dccrpg.html

If anyone reads this blog, any thoughts on dice variety? How much is too much (or too little)?